Ylidenemalononitriles are important synthons in organic chemistry. Substituted pyridines, 4H-pyrane derivatives and pyrazoles that show high biological activity were synthesized on the base of various ylidenemalononitriles. There are formation about synthesis of corresponding polyfunctional dihydroquinoline deri-va¬tives and 5-threefluoromethyl-2,4-dienamides by the reaction of arylethylidenemalononitrile with al¬dehyde and ketones in the presence of base. In some works presented obtaining of chromonyl dienes (or 5,6-dihydroquinoline derivatives) by reaction of arylethylidenemalononitriles with for-myl¬chromones or acethylenic ether in the presence of Et3N and in dichloromethane (or ethanol) media. Also there was carried out the Michael addition reaction of arylethylidenemalononitriles with nitroolefines and by the sequent tandem reaction, the one-pot synthesis of polysubstituted benzene derivatives were obtained. In this work at first time presented the synthesis of substituted isoquinoline derivatives by interaction of various substituted arylethylidenemalononitriles with acetoacetanilide. By NMR investigation it was established that isoquinoline derivatives synthesized in polar solvent are in tautomeric form. Structures of synthesized compounds confirmed by 1H and 13C NMR-spectroscopy and X-Ray analys methods.
Farid Nadir Naghiyev is senior reseacher in scientific laboratory of “Thin Organic Synthesis” of Baku State University. In 2002, he got bachelor and in 2004 master degree. He defended a PhD thesis in 2007. In 2017, he attained assistant professor in the field of organic chemistry. He is the author of 40 articles and 1 patents.
The acetophenones and their derivatives are important intermediates in organic synthesis. They serve as starting material for the synthesis of a variety of heterocyclic compounds that are of physiological significance. Due to their different functionality these compounds confer biological activities, such as antimicrobial, antibacterial, antifungal, anticancer, antitubercular, antiviral, antiinflam¬ma¬tory, antihyperglycemic, and etc. Synthesis, antibacterial and antifungal investigations of new hydroxyacetophenone de¬ri¬va¬ti-ve have be¬en carried out. Structure and dynamics processes in so¬lu¬ti¬ons have confirmed by NMR and in solid state X-Ray methods. The synthesized compound contain hydroxyl, carbonyl groups, bromine atom, aromatic rings and unsaturated bonds. The behavior of such molecule in solutions as well as the presence or absence of molecular associations and dynamic processes are of con¬si¬de¬rab¬le theoretical and practical interest. This concerns, particularly, the dynamic transitions in solutions for compound with pharmaceutical potential like cyclohexenone derivative. The NMR line shape is sensitive to temperature and chemical exchange processes. To get insight into intra- and intermolecular dynamics of this system, we have applied DNMR methods to new cyclohexenone derivative. The synthesized compound was demonstrated poor antifungal properties, but good an¬ti¬bac-te¬rial activity at different dynamic conditions. The compound as powder (at absence of tautomeric transitions) was demons¬trated good sorp¬ti¬on properties against C. bacteria, good an¬ti¬bac¬te¬ri¬al activity against S. aureus and P. aeroginosa in DMSO solution (at presence of tautomers mixture).
Ibrahim Garib Mammadov, professor of Baku State University. In 1997, he graduated from Baku State University. He has worked at the Faculty of Chemistry, BSU, ever since. In 2004, he defended a PhD thesis and a doctoral thesis in 2011. In 2012, he attained professorship in the field of organic and petrol chemistry. He is the author of 180 articles, 6 bo¬¬¬¬oks and 10 patents. He studies phy¬sical and che¬mi¬cal properties of solutions through the NMR spectroscopy. Ibrahim Mammadov for the first time studied molecular dynamics of so¬lu¬tions of new phenols, chalcones derivatives to achieve some interesting results
Mn3O4 (M) incorporated graphenes (G) synthesized by deposition-solvothermal process; formed at various nominal weight percentages (G1M1, G3M1 and G1M3), were thoroughly characterized using XRD, TEM-SAED, UV-Vis diffuse reflectance, N2 sorptiometry, FTIR and Raman techniques. These nanocomposites were tested as supercapacitors via employing cyclic voltammetry, galvanostatic charge-discharge and impedance spectroscopy with reference to the pristine Mn3O4 of spherical-like structure (15 nm). Among the samples, G1M3 of three-dimensional array (26 nm) and accompanied with Mn2O3 moieties; alongside the prominent existence of Mn3O4, exhibited a considerably high specific capacity of 592.7 F g-1; the highest ever reported for Mn3O4 containing materials, at a scan rate of 100 mVs-1 in a threeelectrode system using 1.0 mol L−1 Na2SO4 electrolyte. Furthermore, this nanocomposite achieved remarkable energy density of 72.9 Whkg–1 and a high power density of 1250 Wkg–1 as well as tremendous cycling stability of zero% loss after 1,000 cycles, benefitting grand capability for energy storage applications. This was due to greater surface area (130 m2g-1), pore volume (0.0941 cm3g-1), disperse-ability and to the occurrence of Mn3O4 nearby graphene surfaces facilitating and shortening charges diffusion processes. Although G1M1 and G3M1 samples expose strong intimate interaction between Mn3O4 and graphene exceeding G1M3; as established via TEM-SAED, FTIR and Raman, they exhibit lower specific capacitance values comprised, respectively of 465 F.g-1 and 384 F.g-1. Impedance measurements of the former samples confirmed that their electrodes provide more resistance for ions and electrons and rather weaken by the facile restacking of their graphene sheets unlike G1M3 those own different oxides functionalized graphene that were amenable for increasing the ionic conductivity. It seems that graphene ordering in G1M3 as elaborated via XRD and Raman results as well as the plenty of oxygen moieties on its surface share well in enhancing the specific capacitance; via elaborating hybrid capacitors, together with the unique 3D array of Mn3O4.
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