Dysfunctionalities in autophagy of cancer cells
Aurelian Udristioiu, M.D,Primary Physician, EuSpLM,City Targu Jiu, Romania National Academy of Biochemical Chemistry (NACB) Member, Washington D.C, USA. Fellow PhD in Molecular Biology, Titu Maiorescu University, General Medicine Faculty, Bucharest, Romania. Man of Medical Year/2015 at the International Bibliographic Center, IBC, Cambridge, UK.
Autologous Fat Grafting to the Post Mastectomy Irradiated Chest Wall a New Way for Minimal Invasive Breast Reconstruction a Series of 54 Patients
The Role of Mass Spectrometry in Improving the Diagnosis and Treatment of Hypothyroidism
Dr. Soldin earned his honors degree in Chemistry at the University of Witwatersrand in South Africa where he subsequently received his Master’s degree in Organic Chemistry, and also his PhD in Biochemistry. He enrolled and obtained his boards in Clinical Chemistry at the University of Toronto and then accepted a tenured professor position at the University of Toronto in Clinical Biochemistry and Pharmacology. During his work in Toronto, Dr. Soldin developed new procedures, based on the pressure-harnessing technology known as high-performance liquid chromatography (HPLC), to effectively and sensitively tease out, one by one, disease markers and drugs. Over the years, first in Toronto and later at Children's National Medical Center and George Washington School of Medicine in Washington, D.C., he used this approach to advise physicians on the treatment of patients with a host of diseases—epilepsy, AIDS, heart disease, and cancers such as neuroblastoma or pheochromocytoma. In 1988, Dr. Soldin accepted the position of Director of Clinical Chemistry at Children's National Medical Center in Washington, D.C. As he was developing his tandem mass spec work, he moved to the Clinical Research Center at Georgetown University as Director of their Mass Spectrometry Core facility, where he still serves as Adjunct Professor in the Department of Endocrinology and Metabolism. Starting 2011, Dr. Soldin became a full time Senior Scientist at the Clinical Center Department of Laboratory Medicine where he additionally holds the position of a Deputy Director of Chemistry and Director Post-Doctoral Training Program and the laboratory Mass Spectrometry facility.
Difficult challenges in liver diseases in pregnancy : a treatment-oriented review
Jacques Bernuau has completed his MD in Paris University. He served as an Assistant Professor in clinical hepatology in the Liver Unit, in Hôpital Beaujon, Clichy, France. He also worked as a hepatologist in the gynecology and obstetrics department of the same hospital. He has published several papers on the topic of liver disease in pregnancy in international journals.
HPV, Human Papilloma Virus and cervix cancer
Franco Borruto has completed his PhD and postdoctoral studies from University of Verona, Italy. He now lives in Montecarlo, Principality of Monaco, member of “Ordre des Medecins” of Monaco, Consultant in Health Policy of the Government of Monaco, and Emeritus Member of the International Papilloma Virus Society. He has published more than 200 papers in reputed journals and books and has been serving as an editorial board member of repute.
Aberrant DNA methylation potentiates oncogenes’ expression and disease progression in ovarian cancer
Dimcho Bachvarov, Professor at Université Laval, Québec PQ Canada, grew up in Bulgaria and received his B.Sc. and M.Sc. degrees from the University of Sofia in 1975-1978. He obtained his Ph.D. degree in 1986 in the Institute of Molecular Biology at the Bulgarian Academy of Science. In 1990, he joined Professor Tom Moss's Laboratory at Université Laval as a Postdoctoral Associate, and in 1994 he was appointed as Adjunct Professor at the Dept. Pharmacology, Université Laval. Consecutively, Dr. Bachvarov was promoted to Assistant Professor (1997), Associate Professor (2002) and since 2005 he is a Full Professor at the Dept. Mol. Medicine, Université Laval. He has been a recipient of different Scholarship Awards, with the most representative being the Ernest J.B. Tomlinson Scholarship Award from the Kidney Foundation of Canada and two consecutive Scholarship Awards (Junior and Senior) from Fonds de recherche du Québec - Santé (FRQS). Dr. Bachvarov is strongly involved in the research activities of the provincial Cancer Research Network (CRN), supported by FRQS, as he is the head of the CRN ovarian tumor bio-bank and the CRN genomic platform in Québec City. Currently Dr. Bachvarov’ research interests are focused on the characterization of novel epigenetically regulated epithelial ovarian cancer (EOC) oncogenes and their role in EOC dissemination, as well as the role of EMT and aberrant glycosylation in EOC progression.
Cardiovascular Disease is the Under-Appreciated Primary Health Problem for Women: A Review of the Evidence
Professor Mark Woodward is one the world’s most widely published and cited biostatistician/epidemiologists. He is the author of over 600 peer-reviewed publications, including 6 with over 1000 citations and 14 with 500 or more. He has also published two textbooks on statistical methods in medical research, one of which is a standard text in public health courses at several universities. Mark has played a leadership role in many landmark research projects, particularly in the area of cardiometabolic diseases. While his work covers a broad landscape, the areas in which he has made especially notable contributions include: the prevention of complications of diabetes; the epidemiology of cardiovascular diseases in Asia; sex differences in the effects of cardiovascular risk factors on disease incidence; and the causes and outcomes of renal disease. Mark is a Professor at Oxford University and the University of New South Wales, and Adjunct Professor at Johns Hopkins University.
Professor Osmar Antonio Centurión, is a cardiologist with expertise in Coronary Heart Diseases and Cardiac Arrhythmias, Hemodynamics and Electrophysiology and Arrhythmia Ablation. He is Professor of Medicine at the School of Medical Sciences from the Asuncion National University in Asunción, Paraguay. He received is PhD degree in Cardiology, at the Nagasaki University School of Medicine, Nagasaki, Japan in 1994. He is the Founding Member of Sociedad Latinoamericana de Cardiología Intervencionista (SOLACI). Author of more than 200 medical articles published in peer-reviewed American, European and Japanese journals in cardiology. His biography is published in "Who is Who in the World", "Who is Who in Science and Engineering", "Man of Achievement", "Who is who in Medicine and Healthcare". He is a Fellow of the American College of Cardiology, American Heart Association, and member of other 10 International Cardiovascular Societies. He is currently Chief of the Department of Cardiology, Hospital de Clinicas, Asunción, Paraguay. In addition, He is the Director of the Department of Health Science Investigation at the Metropolitan Hospital, Fernando de la Mora, Paraguay. He is currently Member of the Editorial Board of more than 50 international scientific journals. The following are just some of the cardiovascular international journals: Angiology, JAFIB, Journal of Atrial Fibrillation, The Open Cardiovascular Medicine Journal, Research in Cardiovascular Medicine, The Open Atherosclerosis and Thrombosis Journal, World Journal on Cardiovascular Disease, Hematology and Leukemia, Cardiology and Angiology: An International Journal, Journal of Pharmaceutical Technology & Drug Research, Journal of Bioequivalence & Bioavailability. He is Past-Editor-In-Chief of the Revista de la Sociedad Paraguaya de Cardiología, and current Editor-in-Chief of Mathews Journal of Cardiology, Blood, Heart and Circulation Journal, and Medplus Journal of Experimental Cardiology and Research.
Promoting Cancer Literacy among Black, Latina and Arab Women using the Kin Keeper
Dr. William’s research interest is in cancer prevention and control which focuses on cancer disparities. She developed the Kin Keeper Cancer Prevention Intervention to addresses, in part, the continuous cancer burden carried by disenfranchised women of color and women with limited resources. Targeting breast and cervical cancers, the Kin Keeper intervention has been implemented and tested with Black, Latina and Arab women. She is also interested in how families and various culturally-specific networks can be engage in cancer prevention and control.
Branca M. Silva has completed her Ph.D in Pharmaceutical Sciences (Nutrition and Food Chemistry branch) from the Faculty of Pharmacy – University of Porto (Porto, Portugal) in 2005. Currently, she is an Associate Professor at the Faculty of Health Sciences – University of Beira Interior (Covilhã, Portugal). She is (co)author of about 100 scientific papers and book chapters, has more than 3650 citations and an h-index of 33. Her research interests are oriented to the Medicinal Phytochemistry, Food Chemistry and Nutrition areas. Currently, she is an Academic Editor of the Journal of Chemistry (Hindawi Publishing Corporation). She is also Editorial Board Member and reviewer of several international journals and co-editor of 2 books (Bentham Science Publishers).
The Service Learning Project: An Educational Resource for Medical Students, Physicians and Vulnerable Populations
Prof. Lap Ah Tse (Shelly) has completed her PhD from the Chinese University of Hong Kong and further training at National Cancer Institute, USA. She is the director of Center for Occupational and Environmental Health Studies, head of Division of Occupational and Environmental Health, vice president of Hong Kong Institute of Occupational and Environmental Hygiene. She has published more than 170 papers in reputed journals. Shelly’s research interest is shift work/circadian rhythm and breast/prostate cancer, lung cancer and environmental health impacts of endocrine disrupting chemicals.Abstract
Breast cancer is the top cancer incident and the third leading cancer death in Hong Kong women. The sharply increased age-standardized incidence rate over the past 3 decades cannot be explained by established risk factors including reproductive history and westernized lifestyles (such as, high energy food intake), which indicates that other environmental risk factors may have contributed to the rising trend. Growing evidence showed that some metabolic consequences induced by nighttime eating behavior that may increase breast cancer risk. This study aims to investigate the associations between circadian rhythm interrupted by late nighttime eating and breast cancer risk among Hong Kong women.We also examined whether circadian rhythm disruptioninduced by sleep/wake cycle affects prognosis of breast cancer among women receiving chemotherapy. Based on 922 breast cancer incident cases and 913 hospital controls, we observed habitual nighttime eating after 10pm was significantly associated an adjusted odds ration of 1.50 (95% confidence interval [CI]: 1.06-2.12),while the adjusted odds ratio became higher (2.28, 95%CI: 1.13-6.99) for those with 20 years or longer of such habit as well as those had late eating habit during midnight-2am (adjusted OR=2.73, 95% CI: 1.01-6.99).Regarding association between circadian disruption and breast cancer prognosis among those receiving chemotherapy, we found that those having poor circadian rhythm had high risks to develop Grade 4 neutropenia fever than those with robust rhythm. Results from the case-control study and the subsequent prognostic cohort study suggest an important role of circadian rhythm in breast cancer risk and prognosis.
Dr. Vandana Abramson received her undergraduate degree in English and Molecular & Cell Biology from the University of California. She then attended medical school at the University of Chicago Pritzker School of Medicine. She completed her residency in Internal Medicine at the Brigham and Women’s Hospital/ Harvard Medical School, and subsequently received subspecialty training in Hematology/Oncology at the University of Pennsylvania. Dr. Abramson’s research interests include novel therapeutic treatments for triple negative breast cancer. She has published over 60 peer reviewed articles and has bee the principal investigator of numerous phase I/II clinical trials.Abstract
“Triple negative breast cancer” (TNBC) is a term used to identify the approximately 15% of invasive breast cancers which lack the expression of estrogen and progesterone receptor (ER/PR) and HER2 (ERBB2). TNBCs are a particularly aggressive group of breast cancers; they are generally of a higher grade, occur at a higher rate in young and African-American women, often metastasize to visceral organs early in the disease course, and patients with TNBC have an increased likelihood of distant recurrence and death compared with women with other types of breast. Although aggressive adjuvant chemotherapy, a significant number of early stage TNBCs relapse, often with visceral metastases. In the metastatic setting, despite multiple options for cytotoxic chemotherapy, disease progression is quick, and the median survival of patients with metastatic triple-negative breast cancer is less than two years. Triple-negative breast cancer (TNBC) is a heterogeneous disease; gene expression (GE) analyses recently identified four distinct TNBC subtypes, each displaying a unique biology. Exploring novel approaches to treatment of these subtypes is critical, since less than 30% of women with metastatic breast cancer survive five years and virtually all women with metastatic TNBC will ultimately die of their disease despite systemic therapy. To date, not a single targeted therapy has been approved for the treatment of TNBC and cytotoxic chemotherapy remains the standard treatment. We talk will discuss the current and upcoming therapeutic strategies being explored in an attempt to “target” TNBC.
PREVINE WOMEN: INTEGRAL ATTENTION AND ONCOLOGICAL SCREENING IN A SELF-MANAGEDBiography
MariaLuiza Barros Fernandes Bezerra - Family and Community Physician, Graduate Geriatrics, Master in Psychology. Coordinator of the BRB Health Clinic. Professor at the University of Brasília-UNBAbstract
The program focused on primary care. The gateway is the family doctor and the gynecologist, who receive the support of the interdisciplinary team. The data were analyzed in Epi info 7.2. The test used chi-square and p <0.05. The sample comprised 2,017 participants in the period from 01/01/15 to 06/30/2018. There were 3,561 cervical screening, 128 were considered altered and none culminated in chemotherapy or radiotherapy. There were 2,775 stool occult blood tests and 698 colonoscopies. Eight cases of colon cancer with colectomy indication were observed, four of them with chemotherapy and complementary radiotherapy. There was a significant correlation between women over 40 years of age who were followed up in the clinic with a diagnosis of colon cancer that resulted in surgical treatment and chemotherapy / radiotherapy (8) and followed up in the external network (1), p <0.02. 2,848 mammograms were performed. There was a significant number of women diagnosed with breast cancer and submitted to chemo and radiotherapy treatment (34) and women, diagnosed and treated, followed up in the external network (14), p <0.02. 396 IUDs were implanted. Regarding mental health, 42% of the participants were followed up. Regarding cardiovascular risk, 76% of the women were classified as low, 16% average and 8% as high or very high. There was an 18% decrease in the number of days of work withdrawal due to diseases that were sensitive to the primary care of the participants one year before entering the program.
Inflammatory Breast Cancer among African American Women with Type 2 Diabetes taking Metformin and/or SulfonylureasBiography Abstract
Purpose: This study compares Metformin and sulfonylureas used to treat Type 2 Diabetes and their effect on the prevalence of Triple negative breast cancer in AA women. Methods: A retrospective study was conducted to determine the prevalence of breast cancer in African American women currently treated for their type 2 diabetes with Metformin and/or sulfonylureas. Women ages 38-89 years of age who presented for routine eye exams at The Eye Institute from 2014-2016 and with a diagnosis of Type 2 Diabetes mellitus were included. Women diagnosed with breast cancer less than one year after the Diabetes diagnosis were excluded (n=40), a total of 350 subjects meeting these criteria were identified and classified into one of four groups; Metformin only n=191, sulfonylureas only n=84, both metformin and sulfonylureas n=43 and diet controlled treatment as a control group n=32. Fisher exact test as well as Chi square was used with and without Yates correction to determine an association between these groups. Results: A history of metformin use compared to no metformin cases and controls use was associated with a 3.32 times decreased risk of the presence of breast cancer (p<0.01 for both Chi Square and Fisher Exact test). This association was statistically significant. For subjects using sulfonylureas there was no difference between the sulfonylureas only group and no sulfonylureas group for breast cancer rates. Conclusion: The results of this study supports previous work indicating that Metformin may be protective against comorbidities associated with diabetes, especially those associated with inflammation.
Overweight and lower age at menarche: evidence from the italian HBSC cross-sectional surveyBiography Abstract
Background: A unique standardized national data set from adolescent girls (21 regions) participating to the Italian Health Behaviour in School-aged Children Study (HBSC) was used to investigate the correlation between body mass index (BMI) and age at menarche. Methods: Two independent nationally representative survey data sets from 15-year-olds (n=6907, in 21 regions, year 2013/2014) and 11-year-olds (n=10128, in 20 regions, year 2009/2010) were analyzed. The survey instrument is a self-report questionnaire. Median age at menarche and 95% confidence intervals (CIs) were estimated using Kaplan–Meier analysis. Hierarchical models were used to assess the relationship between BMI and age at menarche (months). “Region-level obesity” was measured by prevalence of overweight/obesity (%) in each region. Results: Region-level median age at menarche ranged between 12 years/ 3 months and 13 years/ 4 months. Region-level prevalence of overweight among 15-year-old girls ranged between 4% and 19%. Age at menarche was inversely associated with individual BMI (unstandardized regression coefficient beta= -0.70; 95% CI, -0.84 to -0.56). Individual- and class-level measures of BMI account for 50% of the region-level variance in age at menarche. Conclusions: The findings add to the evidence that obesity in childhood is a risk factor for early puberty in girls and accounts for much of the cross-national variation in age at menarche. Future HBSC surveys can track this relationship in the wake of the obesity “epidemic.”
Burden of Gene Mutations in Caribbean Women with Breast CancerBiography
Gordon Moffat has his experience if Life Sciences with an Honors in Biology with training in Radiology. His passion for science and interest in microbiology lead him to pursue and obtain a Doctor of Medicine. Currently he is working at the State University of New York Brooklyn Health Sciences Center in Internal Medicine and the forthcoming Medicine Chief Resident. His professional interests include: Medical Oncology, Hospice and Palliative Medicine, and Geriatric Medicine. He is currently working on research projects at Memorial Sloan Kettering Cancer Center in Manhattan, New York that are expected to be published. He is also a candidate for the Alpha Omega Alpha Honor Medical Society Postgraduate Fellowship Award.Abstract
Purpose of Study: Identifying mutations in breast cancer genes (BRCA1/2, PABL2) has important clinical implications on a woman's lifetime susceptibility for breast cancer development. Nearly 10% of immigrants to the United States come from the Caribbean and few studies exist that examine breast cancer gene mutations in African-Caribbean women with existing breast cancer. The purpose is to review breast cancer epidemiology statistics and prevalence of breast cancer genetic mutations in this cohort. Summary of Results Although breast cancer cumulative incidence risk of Caribbean women (5-9%) appear to be less than that of the US women (10%), the cumulative mortality risk in the Caribbean cohort (up to 2.7%) appears greater than that of the US (1.6%). Through a PUBMED literature search, we have also identified five cross-sectional cohort studies on breast cancer patients of Caribbean women who have undergone genetic mutation testing for BRCA1/2 and PALB2 with 27% cases in Bahamas (N=214 women); 2.8% cases in Jamaica (N=179 women); 10.4% cases in Trinidad/Tobago (N=268 women); none in Barbados (N=118 women); 2.6% in Cuba (N=307 women). No study accounted for ascertainment bias. Conclusions This study summarizes the estimate of breast cancer incidence and mortality in Caribbean women and known prevalence of BRCA1/2 and PALB2 breast cancer gene mutations in this cohort. This is critical as part of a formal genetic risk assessment and counseling of patients with breast cancer. Further research and understanding the contributions of inherited gene mutations will guide the optimal health policy in breast cancer screening and risk management.
The Association Between Vitamin D Deficiency in The First Trimester Of Pregnancy And Bacterial VaginosisBiography
DrNermeen El Beltagy MD, PhD, MS, MPH, Professional C is a Professor of in the Department of Obstetrics and Gynecology, Alexandria University, Egypt. She is a member of the International weight management in pregnancy (I-WIP collaborators of the European Union). She received her medical degrees from Egypt, but the PhD in environmental health, and MPH in epidemiology degrees were from Saint Louis University in the USA. She earned her Professional Certificate in women's heath from Exeter University, UK. She authored and coauthored over 10 peer reviewed publications mainly on the subjects of Causes and recommendations of Maternal mortality and morbidity in Egypt, preeclampsia, maternal obesity and contraception. She is an editor of the American journal of cancer prevention.Abstract
Purpose: The aim of the present study was to evaluate the association between vitamin D deficiency and bacterial vaginosis in the first trimester of pregnancy. Methods: acrossection study was conducted on 100 pregnant women attending Elshatby Maternity University Hospital during their first antenatal visit between April - December 2014 (6 months). Women were subjected to a pelvic speculum examination at the initial obstetrical visit to ascertain for the presence of BV and vaginal swab was taken to be evaluated by Gram’s stain for presence of bacterial vaginosis. Plasma 25-OH-D concentration, the major circulating form of vitamin D, was assayed using a commercially available ELISA kit. Results: Our results found that, the age of the included pregnant woman ranged from 20-32 with a mean of 24.9±2.91 years, most of the studied women were less than or equal 25 years (60.0%). The gestational age ranged from 8.0-12.0 weeks with a mean of 9.93±1.59 weeks. Most of the studied women had a BMI more than 25 kg/cm2 (95.0%). 82 cases were positive for bacterial vaginosis, while the other 18 cases (18%) were negative for bacterial vaginosis. The majority of the patients had vitamin D deficiency (53.0% of the patients), while 35.0% of them had insufficient vitamin D. Only 12 cases (12.0%) had sufficient amount of vitamin D. The level of vitamin D ranged from 1.54-40.0 IU with a mean of 13.97±9.57 IU. There was a significant low level of vitamin D deficiency among the cases of bacterial vaginosis. Conclusions: There was an association between vitamin D deficiency in the first trimester of pregnancy and bacterial vaginosis, all women with sufficient serum level of vitamin D were free from bacterial vaginosis compare those with deficient serum vitamin D level.
Inail contribution to gender medicine and to differencesintegration in riskassessmentBiography Abstract
The gender mainstreaming is important from the different repercussions that diseases can cause in women rather than in men at the work too.In Italian laws concerning health and safety at work, mainly Legislative Decree no. 81/2008, gender, age, geographical origin and contractual condition, become important aspects to be considered in order to ensure "uniformity of protection for female and male workers throughout the country through the respect of the essential levels of benefits relating to civil and social rights.It leads the employer toward the drafting of the risk assessment document in a gender perspective, to finally reach the gender integration of Occupational Health and Safety Management Systems (SGSL). For several years,the Italian Workers' Compensation Authority(Inail) has been involved in the collection of accidents at work and occupational diseases data, having regard to the gender difference. In this contest statistical data on accidents at work and occupational diseases reported to Inail in the last five years in the Inail Statistical Database have been analyze. These data are useful in the risk assessment, thatmust take into account all the factors, at both bio-physiological and cultural side, that can interact with certain agents or hazardous conditions and with perception itself of risk. Only by considering all these aspects in a multidimensional way it will be possible to take preventive measures and appropriate protection for risk management in a gender perspective.
Hope For People Living With Metastatic Breast CancerBiography
Aditya Manna has completed his under graduate degree from Vidyasagar University, India and psyco-oncology training from UICC. He is the founder president & chief caregiver of Narikeldaha Prayas, a non profit Organization for cancer palliative care in rural West Bengal, India. He has published more than 16 papers in natational and internationallyAbstract
Introduction: As in any developing countries state of West Bengal in India has a huge burden of metastatic breast cancer patients in advanced stage coming from rural area where awareness regarding the usefulness of palliative care in rather poor. Our goal is to give a pain free good quality of life in these advanced stage breast cancer patients. Method: Advanced breast cancer patients in need of palliative care in various villages in of rural India were selected for this study. Their symptoms and managements in that rural surroundings were evaluated by an NGO (under the guidance of a senior palliative care specialist) working in that area. An attempt was made to identify the main obstacles in getting proper palliative care in a rural setting. Results: Pain, fatigue are the main symptoms effecting these patients. In most patients pain and other symptoms control were grossly inadequate due to lack of properly trained manpower in the rural India. However regular homecare visits by a group of social workers were of immense help in the last few months of life. NGO team was well guided by a palliative care specialist. Conclusion: There is a wide gap of trained manpower in this filled in rural areas of India. Dedicated groups from rural area itself need encouragement, repeated home visit, awareness built up, proper training to home care giver, so that difficult symptoms can be managed locally along with necessary social and psychological support to these patients.
THE HEALTH OF WOMEN IN AFRICABiography
Sylvain HABA born on July 10th / 1963 in Kpoulo (N'Zérékoré Region) Primary 1972-79 1979- 1982 College 1982- 1984 High School Admission to the Baccalaureate in 1984, guidance for school nurses 1985-1988. 1989- 1997 of internships in a medical post at Sèbètèrè Préfecture de Gaoual. 1992-1993 Distance training on medical semiology. In 1998 admitted for service to the public service 2004-2005 Training in traditional medicine in DR Congo. Back Guinea in 2006 creation of the Talithakoumi Spiritual Traditional Medical Care Center (Marc5: 41-42) in (Labe) Guinea. In 2008 transfer from the center to ConakryAbstract
Puerperal craziness or pregnancy intoxication Women in Africa after early marriage, the risk of female circumcision and sometimes the lack of immunization coverage are also vulnerable to a lack of antenatal care, which is often the cause of headaches, vertigo, tinnitus, edema, symptoms of hypertension, albuminuria usually making it difficult for the last six months of pregnancy. Traditional birth attendants, or those who have benefited from training with doctors or nurses, often alert families or environments where there are no health workers, they use plants as a diuretic and impose the salt-free and protein-free diet. , without excitement. Here are the plants used: A -like diuretic 1. Combretum micranthum F: combretaceae 5 to 10g leaves in decoction drunk by will for 4 days 2. Bridélia ferruginéa F: ephorbiaceae 3 to 5g of bark by maceration for 1 to 4 days B-Plants given in tranquilizing 1. Maniot Utlissma F: Euphorbiaceae 1 to 2 crushed tubers 1 to 2 liters by maceration, drink after 5 pm in the evening 2. Rauwolfia Vomitaria F: Apocynaceae 2 to 5 pinches of washed bark, dried to take in the evening. The monitoring elements (blood pressure, temperature, weight, pulse) will be taken into account
Impact of Mmastectomy on Qquality of Llife in Ffemale Bbreast Ccancer Ppatients in the Gaza Strip: a Ccross Ssectional-SstudyBiography
Enas Alaloul has completed her M.D. in the Islamic Univeristy in Palesine in 2017 and right now, on her Master’s degree in University of Leeds- United Kigdom. She has published more than 16 abstract- papers in reputed journals.Abstract
Background: The quality of care for breast cancer sufferers after mastectomy should be designed with long term goals to ensure the physical, psychological and social well-being of survivors. This study explores the impact of mastectomy on the quality of life among breast cancer survivors after mastectomy in the Gaza-Strip. Methods: This is a multicenter (why not say how many hospitals/clinics were involved?) cross-sectional study in which 173 patients who underwent mastectomy in the Gaza Strip (how were they chosen?) completed a face-to-face questionnaire with five sections: socio-demographic data, physical, psychological, social well-being and family dynamics. Data were collected from August 2015 to September 2016. For data analysis, SPSS software (version 21) was used. Ethical approval from the Palestinian Ministry of Health and written consent from patients were obtained. Results: The mean age (at interview?) was 51.0 ±10.0 years. In total, 73.0% (n=126) had low educational achievements (less than 12 years of education), 91.0% (n=157) were unemployed and 20.8% (n=36) had a first-degree relative with breast cancer. Two thirds (n=133) had undergone radical mastectomy, while 17.0% (n=29) had breast-conserving surgery. in evaluating the negative impacts of mastectomy, psychological well-being was the most affected domain (66.4%), followed by physical well-being (52.2%), social well-being (44.2%) and family dynamics (49.2%). After their mastectomy, 57.2% (n= 99) were fatigued, 48.6% (n=84) suffered from early menopausal symptoms and 42.8% (n=74) had sleep disturbances. Feeling worried was the most identified psychological complaint (n=91, 52.6%). Furthermore, 55.5% (n=96) of patients experienced financial impact and 59.0% (n=102) had decreased home activities. Interestingly, 165 (95.4%) were not worried about divorce due to their surgery. Interpretation The great fear of divorce found in this study demonstrates the insecurity of women within Gazan society. Involving the patient’s family in the process of medical and supportive care is important to promote social well-being. Improving holistic medical care for breast cancer survivors in the Gaza-Strip is essential.
The Role Of Volunteers In Quality Palliative Care DeliveryBiography
Aditya Manna has completed his under graduate degree from Vidyasagar University, India and psyco-oncology training from UICC. He is the founder president & chief caregiver of Narikeldaha Prayas, a nonprofit Organization for cancer palliative care in rural West Bengal, India. He has published more than 16 papers in natational and internationally.Abstract
Introduction Here in India almost 75% of cancer patient die a sad death of neglect due to lack of awareness about palliative care and low economic level. Surveys in India show that two third of cancer patient do not get proper care during the terminal phase of their life. Palliative care through volunteers can make a significant difference in this respect. Objective To identify and try to solve, to the extent possible, the main difficulties in giving palliative care to the terminal cancer patients of the area. And evaluate the impact of volunteer’s direct care of palliative patients and their families. Methods Feedback from patients and their relatives regarding the palliative care they receive from nursing home and from volunteers and compare the two. Also feedback from volunteers regarding their positive and negative experience while delivering palliative care service. Then evaluate the data to compare and improve the quality of service. Results We carried out two studies. One study was undertaken in nursing home palliative care and another was in home setting by volunteers. Both studies were in adult palliative care services. Since January 2016, 552 cases were studied to enquire about their experience in both home based care and nursing home care. Both the studies fulfilled our quality appraisal criteria. One found that those families and patients who received home visits from volunteers were significantly more satisfied. The study highlighted the value of the role of volunteers in better satisfaction of patients and their families. Conclusions Further research is needed to evaluate the role of volunteers in palliative care and how it can be delivered appropriately and effectively. We also wish to compare our findings with similar studies elsewhere.
Range of motion and upper limb function in postoperative mastectomy compared to quadrantectomyBiography Abstract
Breast cancer is worldwid e incident among women, whose surgery is frequent and associated with numerous functional changes. Objective: To assess the range of motion and upper limb function postoperatively before and after physiotherapy intervention of women who underwent mastectomy and quadrantectomy. Methods: This is interventional study, descriptive and exploratory, quantitative approach, with 64 women undergoing conservative surgery and mastectomy with follow up at the gynecology outpatient clinic and referred for physical therapy at the Hospital das Clinicas, UNESP. Was performed goniometry of flexion / extension, abduction / adduction and internal rotation / side, measures performed before and three months after the herapy. Results: The chi square test with 0.005 significance level showed that quadrantectomy or mastectomy, not differentiated in relation to the variables; schooling, family income, color, marital status, religion, breast affected, clinical staging, menarche, body mass index and contraceptive methods. There was no association between type of surgery and the median age (type 1: 55 (37-57) x 2 type: 54 (37-82), p = 0.331 by Mann-Whitney). Conclusion: After physiotherapy, the flexion of the homo- and contralateral arm, as well as the homolateral abduction and homolateral extension increased significantly in both surgeries. The contralateral abduction was maintained in both surgeries. The physiotherapeutic intervention provided a significant improvement in the range of movements.
Effect of acupuncture on hot flush and menopause symptoms in breast cancer- A systematic review and meta-analysis
Dr. Tsai-Ju Chien is a Hemato-Oncologist as well as a TCM doctor. The unique character of her is that she practices both TCM and western medicine in the same time in clinical for years. She devotes herself in bridging the gap between TCM and main stream medicine. What she focused is not only clinical care but also the basic research. She therefore extends her interest and research from clinical trial to basic study; from TCM herb to acupuncture. She has the passion to coordinate oriental and western medicine by applying modern method and therefore to reconcile the holism and reductionism
The Effect of Vitamin D on Maternal Vitamin D Status and Breast Milk Properties
Carol L. Wagner, MD is Professor of Pediatrics at the Medical University of South Carolina, Charleston, SC, USA, where she works as an academic neonatologist and translational researcher in the area of vitamin D requirements during pregnancy and lactation for more than 18 years. She has published more than 130 papers in reputed journals and has been serving as an editorial board member and reviewer for several journals.
Heme/non-heme iron ratio and breast cancer risk: a case-control study
Dr. Alvaro Ronco (Montevideo, 1958) is a Uruguayan M.D. with large expertise in nutritional epidemiology of cancer, focused on breast cancer. He is Associated Professor of Cancer Epidemiology at the CLAEH University in Uruguay and has published 140 papers in international peer-reviewed specialized journals. Author of Nutritional Epidemiology of Breast Cancer (Springer, Dordrecht 2012), the first book published on this area. Distinguished by AACR as one of the 12 Latin American referent researchers in cancer. He is a Non-EU expert member in the database of the European Commission.
Calcium’s role in preeclampsia prevention may extend to the prevention of long-term maternal risks for hypertension.
Prof. Egeland has expertise in epidemiological methods and analyses of complex data in cross-disciplinary research involving cardio-metabolic diseases, reproduction, and nutritional health. She currently works as Senior Researcher at the Norwegian Institute of Public Health and is Adjunct Professor at the Dept. of Global Public Health and Primary Care, University of Bergen, Norway. She has over 135 publications including book chapters; is currently engaged in registry-based research, and leads several research projects spanning disciplines in life-course epidemiology.
Tumour and lymph node microenviroment in breast cancer patients.
Antigoni Poultsidi is the Lecturer in General Surgery, Faculty of medicine, University of Thessaly, Greece, position at the General Surgery Department in University Hospital of Larisa, Greece
Epitranscriptomic blood biomarkers to manage psychiatric disorders
Dinah Weissmann, PhD is a Founder of Biocortech and also serves as Chairman of the Board and Chief Executive Officer. Dr. Weissmann is an expert in neurobiology, with 20 years' experience in R&D management. Prior to founding Biocortech, she was a Senior Scientist at Roussel Uclaf (now Sanofi-Aventis). Her research background includes an appointment as a Research Director at the CNRS (Center for National Research and Science). She was also a co-founder of the CNRS Neuropharmacology lab at Lyon University. She is the author of 55 scientific publications and 6 patents in the field of neurosciences. She serves as a Director of France Biotech. She received her PharmD and PhD from Strasbourg University, a leading European neurosciences centre.
Dissecting the protective effect of vaginal Lactobacillus towards Chlamydia trachomatis infection
Carola Parolin graduated in Biotechnology at University of Milan-Bicocca, Italy, and completed her PhD at Bologna Univesity, Italy, where she currently works as a post-doc researcher. Her main interests concern human ecology, particularly the vaginal microbiome, and probiotics. She is co-author of 31 scientific publications, and serves as a reviewer for many reputed journals. This research was supported by Fondazione del Monte di Bologna e Ravenna, Italy.
The oral health of pregnant women as a new potential risk factor for prematurity and cardiovascular diseases in children
Senka Mesihović-Dinarević paediatric cardiologist: Faculty of Medicine, University of Sarajevo 1982. 1982-2016. Paediatric Clinic. PhD 1991, 1992-1996: Royal Brompton Hospital London. Professor of Paediatrics 2006.1994. AEPC, 1995. BPCA.1995-2011: Lecturer London MRCP; 2014. Director of Discipline for health protection of women and children. Consultant: RCPCH 1997. 2003-2016. Director of Paediatric Clinic Sarajevo.2000 FESC, 2008. Full Member of Academy of Sciences and Arts of Bosnia and Herzegovina, Honorary Doctorate of Letters in Cambridge: 2014. 2016.Member of the European Academy of Science and Arts; 2017. Full Professor University for Peace-United Nations, over 498 papers, cited 218 times in the ICI Web of Science.
Cyclin Dependent Kinase (CDK) 4/6 Inhibitor Therapy for Breast Cancer
Dr. Maysa Abu-Khalaf is the director of Breast Medical Oncology for the Division of Solid Tumor, and co-director of the Jefferson Breast Care Center for the Sidney Kimmel Cancer Center at Thomas Jefferson University in Philadelphia, PA. She is a medical oncologist with clinical expertise in the management of breast cancer. Her research focus is evaluating novel agents for the treatment of breast cancer and predictive markers of response to these therapies.
The Association between Vitamin D Deficiency and Breast Cancer: A Case-Control Study in Riyadh, Saudi Arabia
Lolwah Alriyees, MBBS, SSC-Surg, ABS, MPH-Epi, Currently working as Consultant General Surgery, Department of surgery, King Abdulaziz Medical City, King Fahad Nation Guard Hospital, Surgery block coordinator and Assistant Professor Of Surgery, KSAU
A Multimodal Approach for Opioid-Free Analgesia After Cesarean Section Using Surgical Site Infiltration With Liposomal Bupivacaine.
Richard Chudacoff, MD FACOG is an obstetrician/gynecologist specializing in Enhanced Recovery after Cesarean Section and Enhanced Recovery after GYN Surgery, and minimally invasive GYN surgery. He trained at the National Naval Medical Center in Bethesda, MD and has held faculty appointments at the Uniformed Services University for the Health Sciences, Bethesda, MD, Baylor College of Medicine, Houston, TX and University of Nevada, Las Vegas, NV.
ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PREVENTIVE PRACTICES TOWARDS SEXULLY TRANSMITTED INFECTION AMONG STUDENTS IN SAMARA UNIVERSITY,AFAR REGION, NORTH EASTERN ETHIOPIA, 2018
Dr.P.Surender Reddy is basically Homoeopathic Medical degree holder .He has Master’s degree in Public Health, Population Studies & PhD in Population Studies with Reproductive health topic. He was a clinician in the very beginning of his carrier. He was the President in a N.G.O called RMHSS for the project of “RCH” funded by World Bank through Government of India. He worked as professor and in other different positions in India and abroad. At present he is working as professor in the department of Public Health, Samara University, Ethiopia.